Multiplexing siRNAs to compress RNAi-based screen size in human cells

Here we describe a novel strategy using multiplexes of synthetic small interfering RNAs (siRNAs) corresponding to multiple gene targets in order to compress RNA interference (RNAi) screen size. Before investigating the practical use of this strategy, we first characterized the gene-specific RNAi ind...

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Detalles Bibliográficos
Autores principales: Martin, Scott E., Jones, Tamara L., Thomas, Cheryl L., Lorenzi, Philip L., Nguyen, Dac A., Runfola, Timothy, Gunsior, Michele, Weinstein, John N., Goldsmith, Paul K., Lader, Eric, Huppi, Konrad, Caplen, Natasha J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885663/
https://www.ncbi.nlm.nih.gov/pubmed/17392344
http://dx.doi.org/10.1093/nar/gkm141

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