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A tractable method for simultaneous modifications to the head and tail of bacteriophage lambda and its application to enhancing phage-mediated gene delivery
There is considerable interest in the use of bacteriophage vectors for mammalian cell gene transfer applications, due to their stability, excellent safety profile and inexpensive mass production. However, to date, phage vectors have been plagued by mediocre performance as gene transfer agents. This...
Autores principales: | Zanghi, Christine N., Sapinoro, Ramil, Bradel-Tretheway, Birgit, Dewhurst, Stephen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885665/ https://www.ncbi.nlm.nih.gov/pubmed/17392341 http://dx.doi.org/10.1093/nar/gkm146 |
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