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Keratinocyte serum-free medium maintains long-term liver gene expression and function in cultured rat hepatocytes by preventing the loss of liver-enriched transcription factors
Freshly isolated hepatocytes rapidly lose their differentiated properties when placed in culture. Therefore, production of a simple culture system for maintaining the phenotype of hepatocytes in culture would greatly facilitate their study. Our aim was to identify conditions that could maintain the...
Autores principales: | Li, Wan-Chun, Ralphs, Kate L., Slack, Jonathan M.W., Tosh, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885942/ https://www.ncbi.nlm.nih.gov/pubmed/17129745 http://dx.doi.org/10.1016/j.biocel.2006.10.017 |
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