p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells

p53 and tau are both associated with neurodegenerative disorders. Here, we show by Western blotting that p53 is upregulated approximately 2-fold in the superior temporal gyrus of Alzheimer's patients compared to healthy elderly control subjects. Moreover, p53 was found to induce phosphorylation...

Descripción completa

Detalles Bibliográficos
Autores principales: Hooper, Claudie, Meimaridou, Eirini, Tavassoli, Mahvash, Melino, Gerry, Lovestone, Simon, Killick, Richard
Formato: Texto
Lenguaje:English
Publicado: Elsevier Scientific Publishers Ireland 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885960/
https://www.ncbi.nlm.nih.gov/pubmed/17399897
http://dx.doi.org/10.1016/j.neulet.2007.03.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885960/
https://www.ncbi.nlm.nih.gov/pubmed/17399897
http://dx.doi.org/10.1016/j.neulet.2007.03.026

Ejemplares similares