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p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells
p53 and tau are both associated with neurodegenerative disorders. Here, we show by Western blotting that p53 is upregulated approximately 2-fold in the superior temporal gyrus of Alzheimer's patients compared to healthy elderly control subjects. Moreover, p53 was found to induce phosphorylation...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Scientific Publishers Ireland
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885960/ https://www.ncbi.nlm.nih.gov/pubmed/17399897 http://dx.doi.org/10.1016/j.neulet.2007.03.026 |