Activated Ras Signals Developmental Progression of Recombinase-activating Gene (RAG)-deficient Pro-B Lymphocytes

To elucidate the intracellular pathways that mediate early B cell development, we directed expression of activated Ras to the B cell lineage in the context of the recombination-activating gene 1 (RAG1)-deficient background (referred to as Ras–RAG). Similar to the effects of an immunoglobulin (Ig) μ...

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Detalles Bibliográficos
Autores principales: Shaw, Albert C., Swat, Wojciech, Ferrini, Roger, Davidson, Laurie, Alt, Frederick W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887686/
https://www.ncbi.nlm.nih.gov/pubmed/9874569

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