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Negative Regulation of T Cell Proliferation and Interleukin 2 Production by the Serine Threonine Kinase Gsk-3
Glycogen synthase kinase (GSK)-3 is a protein serine/threonine kinase that regulates differentiation and cell fate in a variety of organisms. This study examined the role of GSK-3 in antigen-specific T cell responses. Using resting T cells from P14 T cell receptor (TCR)-transgenic mice (specific for...
Autores principales: | Ohteki, Toshiaki, Parsons, Michael, Zakarian, Arsen, Jones, Russell G., Nguyen, Linh T., Woodgett, James R., Ohashi, Pamela S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887707/ https://www.ncbi.nlm.nih.gov/pubmed/10880530 |
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