HIV-Specific Cd8(+) T Cells Produce Antiviral Cytokines but Are Impaired in Cytolytic Function

The use of peptide–human histocompatibility leukocyte antigen (HLA) class I tetrameric complexes to identify antigen-specific CD8(+) T cells has provided a major development in our understanding of their role in controlling viral infections. However, questions remain about the exact function of thes...

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Detalles Bibliográficos
Autores principales: Appay, Victor, Nixon, Douglas F., Donahoe, Sean M., Gillespie, Geraldine M.A., Dong, Tao, King, Abigail, Ogg, Graham S., Spiegel, Hans M.L., Conlon, Christopher, Spina, Celsa A., Havlir, Diane V., Richman, Douglas D., Waters, Anele, Easterbrook, Philippa, McMichael, Andrew J., Rowland-Jones, Sarah L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887711/
https://www.ncbi.nlm.nih.gov/pubmed/10880527

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