H2-DMα(−/)− Mice Show the Importance of Major Histocompatibility Complex–Bound Peptide in Cardiac Allograft Rejection

The role played by antigenic peptides bound to major histocompatibility complex (MHC) molecules is evaluated with H2-DMα(−/)− mice. These mice have predominantly class II–associated invariant chain peptide (CLIP)-, not antigenic peptide–bound, MHC class II. H2-DMα(−/)− donor heart grafts survived th...

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Detalles Bibliográficos
Autores principales: Felix, Nathan J., Brickey, W. June, Griffiths, Robert, Zhang, Jinghua, Van Kaer, Luc, Coffman, Thomas, Ting, Jenny P.-Y.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887714/
https://www.ncbi.nlm.nih.gov/pubmed/10880524

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