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BCMA Is Essential for the Survival of Long-lived Bone Marrow Plasma Cells
Long-lived humoral immunity is manifested by the ability of bone marrow plasma cells (PCs) to survive for extended periods of time. Recent studies have underscored the importance of BLyS and APRIL as factors that can support the survival of B lineage lymphocytes. We show that BLyS can sustain PC sur...
Autores principales: | O'Connor, Brian P., Raman, Vanitha S., Erickson, Loren D., Cook, W. James, Weaver, Lehn K., Ahonen, Cory, Lin, Ling-Li, Mantchev, George T., Bram, Richard J., Noelle, Randolph J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887725/ https://www.ncbi.nlm.nih.gov/pubmed/14707116 http://dx.doi.org/10.1084/jem.20031330 |
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