Mitochondrial Oxidative Stress Causes Hyperphosphorylation of Tau

Age-related neurodegenerative disease has been mechanistically linked with mitochondrial dysfunction via damage from reactive oxygen species produced within the cell. We determined whether increased mitochondrial oxidative stress could modulate or regulate two of the key neurochemical hallmarks of A...

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Detalles Bibliográficos
Autores principales: Melov, Simon, Adlard, Paul A., Morten, Karl, Johnson, Felicity, Golden, Tamara R., Hinerfeld, Doug, Schilling, Birgit, Mavros, Christine, Masters, Colin L., Volitakis, Irene, Li, Qiao-Xin, Laughton, Katrina, Hubbard, Alan, Cherny, Robert A., Gibson, Brad, Bush, Ashley I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888726/
https://www.ncbi.nlm.nih.gov/pubmed/17579710
http://dx.doi.org/10.1371/journal.pone.0000536

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