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RNA polymerase III transcription is repressed in response to the tumour suppressor ARF

The tumour suppressor protein ARF provides a defence mechanism against hyperproliferative stresses that can result from the aberrant activation of oncogenes. Accordingly, ARF is silenced or deleted in many human cancers. Activation of ARF can arrest growth and cell cycle progression, or trigger apop...

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Detalles Bibliográficos
Autores principales:	Morton, Jennifer P., Kantidakis, Theodoros, White, Robert J.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888803/ https://www.ncbi.nlm.nih.gov/pubmed/17439968 http://dx.doi.org/10.1093/nar/gkm208

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