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Sequence analysis of p53 response-elements suggests multiple binding modes of the p53 tetramer to DNA targets
The p53 tetramer recognizes specifically a 20-bp DNA element. Here, we examined symmetries encoded in p53 response elements (p53REs). We analyzed base inversion correlations within the half-site, as well as in the full-site palindrome. We found that p53REs are not only direct repeats of half-sites;...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888811/ https://www.ncbi.nlm.nih.gov/pubmed/17439973 http://dx.doi.org/10.1093/nar/gkm192 |