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CAF1 plays an important role in mRNA deadenylation separate from its contact to CCR4

The CAF1 protein is a component of the CCR4–NOT deadenylase complex. While yeast CAF1 displays deadenylase activity, this activity is not required for its deadenylation function in vivo, and CCR4 is the primary deadenylase in the complex. In order to identify CAF1-specific functional regions require...

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Detalles Bibliográficos
Autores principales: Ohn, Takbum, Chiang, Yueh-Chin, Lee, Darren J., Yao, Gang, Zhang, Chongxu, Denis, Clyde L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888822/
https://www.ncbi.nlm.nih.gov/pubmed/17439972
http://dx.doi.org/10.1093/nar/gkm196