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All APOBEC3 family proteins differentially inhibit LINE-1 retrotransposition

Approximately 17% of the human genome is comprised of long interspersed nuclear element 1 (LINE-1, L1) non-LTR retrotransposons. L1 retrotransposition is known to be the cause of several genetic diseases, such as hemophilia A, Duchene muscular dystrophy, and so on. The L1 retroelements are also able...

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Detalles Bibliográficos
Autores principales:	Kinomoto, Masanobu, Kanno, Takayuki, Shimura, Mari, Ishizaka, Yukihito, Kojima, Asato, Kurata, Takeshi, Sata, Tetsutaro, Tokunaga, Kenzo
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888823/ https://www.ncbi.nlm.nih.gov/pubmed/17439959 http://dx.doi.org/10.1093/nar/gkm181

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