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An adaptation of the LMS method to determine expression variations in profiling data

One of the major issues in expression profiling analysis still is to outline proper thresholds to determine differential expression, while avoiding false positives. The problem being that the variance is inversely proportional to the log of signal intensities. Aiming to solve this issue, we describe...

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Detalles Bibliográficos
Autores principales: Chuchana, Paul, Marchand, Dorian, Nugoli, Mélanie, Rodriguez, Carmen, Molinari, Nicolas, Garcia-Sanz, Jose A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888829/
https://www.ncbi.nlm.nih.gov/pubmed/17459890
http://dx.doi.org/10.1093/nar/gkm093