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Recruitment of DNA repair synthesis machinery to sites of DNA damage/repair in living human cells
The eukaryotic sliding DNA clamp, proliferating cell nuclear antigen (PCNA), is essential for DNA replication and repair synthesis. In order to load the ring-shaped, homotrimeric PCNA onto the DNA double helix, the ATPase activity of the replication factor C (RFC) clamp loader complex is required. A...
Autores principales: | Hashiguchi, Kazunari, Matsumoto, Yoshihiro, Yasui, Akira |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888830/ https://www.ncbi.nlm.nih.gov/pubmed/17439963 http://dx.doi.org/10.1093/nar/gkm115 |
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