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Oral Pirfenidone in patients with chronic fibrosis resulting from radiotherapy: a pilot study

BACKGROUND: Fibrosis is a common side effect after treatment with ionizing radiation. Several methods to ameliorate debilitating fibrosis have been employed but without consistent results. The goal of this pilot study is to determine if Pirfenidone, a novel regulator of cytokine gene expression, has...

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Detalles Bibliográficos
Autores principales: Simone, Nicole L, Soule, Benjamin P, Gerber, Lynn, Augustine, Elizabeth, Smith, Sharon, Altemus, Rosemary M, Mitchell, James B, Camphausen, Kevin A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891306/
https://www.ncbi.nlm.nih.gov/pubmed/17540023
http://dx.doi.org/10.1186/1748-717X-2-19