Antibiotic Resistance Genes Online (ARGO): A Database on vancomycin and β­lactam resistance genes

Vancomycin and β­lactams are antibiotics that inhibit gram positive bacteria by interfering with cell wall synthesis. However, continuous use of antibiotics results in the emergence of multi-drug resistant (MDR) bacterial strains. Here, we describe ARGO, a database containing gene sequences conferri...

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Detalles Bibliográficos
Autores principales: Scaria, Joy, Chandramouli, Umamaheswaran, Verma, Sanjay Kumar
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2005
Materias:
Web Database
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891619/
https://www.ncbi.nlm.nih.gov/pubmed/17597841
Descripción
Sumario:Vancomycin and β­lactams are antibiotics that inhibit gram positive bacteria by interfering with cell wall synthesis. However, continuous use of antibiotics results in the emergence of multi-drug resistant (MDR) bacterial strains. Here, we describe ARGO, a database containing gene sequences conferring resistance to these two classes of antibiotics. It is designed as a resource to enhance research on the prevalence and spread of antibiotic resistance genes. ARGO is the first attempt to compile the resistance gene sequence data with state specific information. AVAILABILITY: AGRO is available for free at http://www.argodb.org/

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