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Protein beta-turn assignments

A classical way to analyze protein 3D structures or models is to investigate their secondary structures. Their predictions are also widely used as a help to build new 3D models. Thus, hundreds of prediction methods have been proposed. Nonetheless before predicting, secondary structure assignment is...

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Detalles Bibliográficos
Autores principales: Bornot, Aurélie, de Brevern, Alexandre G
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891681/
https://www.ncbi.nlm.nih.gov/pubmed/17597878
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author Bornot, Aurélie
de Brevern, Alexandre G
author_facet Bornot, Aurélie
de Brevern, Alexandre G
author_sort Bornot, Aurélie
collection PubMed
description A classical way to analyze protein 3D structures or models is to investigate their secondary structures. Their predictions are also widely used as a help to build new 3D models. Thus, hundreds of prediction methods have been proposed. Nonetheless before predicting, secondary structure assignment is required even if not trivial. Therefore numerous but diverging assignment methods have been developed. β-turns constitute the third most important secondary structures. However, no analysis to compare the β-turn distributions according to different secondary structure assignment methods has ever been done. We propose in this paper to analyze and evaluate the results of such a comparison. We highlight some important divergence that could have important consequence for the analysis and prediction of β-turns.
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spelling pubmed-18916812007-06-27 Protein beta-turn assignments Bornot, Aurélie de Brevern, Alexandre G Bioinformation Views & Challenges A classical way to analyze protein 3D structures or models is to investigate their secondary structures. Their predictions are also widely used as a help to build new 3D models. Thus, hundreds of prediction methods have been proposed. Nonetheless before predicting, secondary structure assignment is required even if not trivial. Therefore numerous but diverging assignment methods have been developed. β-turns constitute the third most important secondary structures. However, no analysis to compare the β-turn distributions according to different secondary structure assignment methods has ever been done. We propose in this paper to analyze and evaluate the results of such a comparison. We highlight some important divergence that could have important consequence for the analysis and prediction of β-turns. Biomedical Informatics Publishing Group 2006-06-08 /pmc/articles/PMC1891681/ /pubmed/17597878 Text en © 2006 Biomedical Informatics Publishing Group This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
spellingShingle Views & Challenges
Bornot, Aurélie
de Brevern, Alexandre G
Protein beta-turn assignments
title Protein beta-turn assignments
title_full Protein beta-turn assignments
title_fullStr Protein beta-turn assignments
title_full_unstemmed Protein beta-turn assignments
title_short Protein beta-turn assignments
title_sort protein beta-turn assignments
topic Views & Challenges
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891681/
https://www.ncbi.nlm.nih.gov/pubmed/17597878
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