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Docking of phosphonate and trehalose analog inhibitors into M. tuberculosis mycolyltransferase Ag85C: Comparison of the two scoring fitness functions GoldScore and ChemScore, in the GOLD software

The Ag85 family enzymes are responsible for the synthesis of cell wall components in mycobacterial species. Inhibitors to these enzymes are potential antimycobacterial agents. We have carried out the docking of phoshonate and trehalose analog inhibitors into the three dimensional structure of mycoly...

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Detalles Bibliográficos
Autores principales:	Annamala, Manoj Kumar, Inampudi, Krishna Kishore, Guruprasad, Lalitha
Formato:	Texto
Lenguaje:	English
Publicado:	Biomedical Informatics Publishing Group 2007
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891722/ https://www.ncbi.nlm.nih.gov/pubmed/17597917

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