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Dynamics of adipogenic promoter DNA methylation during clonal culture of human adipose stem cells to senescence
BACKGROUND: Potential therapeutic use of mesenchymal stem cells (MSCs) is likely to require large-scale in vitro expansion of the cells before transplantation. MSCs from adipose tissue can be cultured extensively until senescence. However, little is known on the differentiation potential of adipose...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892011/ https://www.ncbi.nlm.nih.gov/pubmed/17535427 http://dx.doi.org/10.1186/1471-2121-8-18 |