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A rare case of concomitant huge exophytic gastrointestinal stromal tumor of the stomach and Kasabach-Merritt phenomenon
BACKGROUND: We report an extremely rare case of concomitant huge exophytic GIST of the stomach and Kasabach-Merritt phenomenon (KMP). CASE PRESENTATION: The patient was a 67-year-old man experiencing abdominal distension since September 2006. A physical examination revealed a 25 × 30 cm hard mass th...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892781/ https://www.ncbi.nlm.nih.gov/pubmed/17540038 http://dx.doi.org/10.1186/1477-7819-5-59 |
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author | Watanabe, Taiji Segami, Kohei Sasaki, Takahiro Kawashima, Hatsuya Enomoto, Takeharu Jinnouchi, Yuji Koizumi, Satoshi Tobe, Naotaka Sakurai, Joh Shimamura, Tsukasa Suda, Tadashi Asakura, Takeshi Nakano, Hiroshi Ichiroh, Tanaka Otsubo, Takehito |
author_facet | Watanabe, Taiji Segami, Kohei Sasaki, Takahiro Kawashima, Hatsuya Enomoto, Takeharu Jinnouchi, Yuji Koizumi, Satoshi Tobe, Naotaka Sakurai, Joh Shimamura, Tsukasa Suda, Tadashi Asakura, Takeshi Nakano, Hiroshi Ichiroh, Tanaka Otsubo, Takehito |
author_sort | Watanabe, Taiji |
collection | PubMed |
description | BACKGROUND: We report an extremely rare case of concomitant huge exophytic GIST of the stomach and Kasabach-Merritt phenomenon (KMP). CASE PRESENTATION: The patient was a 67-year-old man experiencing abdominal distension since September 2006. A physical examination revealed a 25 × 30 cm hard mass that was palpable in the middle and lower left abdomen minimal intrinsic mobility and massive ascites. Since the admitted patient was diagnosed with DIC, surgery could not be performed. The patient received a platelet transfusion and the DIC was treated. Due to this treatment, the platelet count recovered to 7.0 × 10(4); tumor resection was performed at 16 days after admission. Laparotomy revealed a huge extraluminal tumor arising from the greater curvature of the stomach that measured 25 × 30 cm and had not ruptured into the peritoneal cavity or infiltrated other organs. Partial gastric resection was performed. The resected mass measured 25 × 25 × 20 cm. In cross section, the tumor appeared hard and homogenous with a small polycystic area. Histopathology of the resected specimen showed large spindle cell GIST with >5/50 HPF (high-power field) mitotic activity. The postoperative course was uneventful, and the coagulopathy improved rapidly. CONCLUSION: Since the characteristic of tumor in this case was hypervascularity with bleeding and necrotic lesions, coagulopathy was thought to be caused by the trapping of platelets within a large vasculized tumor mass. |
format | Text |
id | pubmed-1892781 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-18927812007-06-18 A rare case of concomitant huge exophytic gastrointestinal stromal tumor of the stomach and Kasabach-Merritt phenomenon Watanabe, Taiji Segami, Kohei Sasaki, Takahiro Kawashima, Hatsuya Enomoto, Takeharu Jinnouchi, Yuji Koizumi, Satoshi Tobe, Naotaka Sakurai, Joh Shimamura, Tsukasa Suda, Tadashi Asakura, Takeshi Nakano, Hiroshi Ichiroh, Tanaka Otsubo, Takehito World J Surg Oncol Case Report BACKGROUND: We report an extremely rare case of concomitant huge exophytic GIST of the stomach and Kasabach-Merritt phenomenon (KMP). CASE PRESENTATION: The patient was a 67-year-old man experiencing abdominal distension since September 2006. A physical examination revealed a 25 × 30 cm hard mass that was palpable in the middle and lower left abdomen minimal intrinsic mobility and massive ascites. Since the admitted patient was diagnosed with DIC, surgery could not be performed. The patient received a platelet transfusion and the DIC was treated. Due to this treatment, the platelet count recovered to 7.0 × 10(4); tumor resection was performed at 16 days after admission. Laparotomy revealed a huge extraluminal tumor arising from the greater curvature of the stomach that measured 25 × 30 cm and had not ruptured into the peritoneal cavity or infiltrated other organs. Partial gastric resection was performed. The resected mass measured 25 × 25 × 20 cm. In cross section, the tumor appeared hard and homogenous with a small polycystic area. Histopathology of the resected specimen showed large spindle cell GIST with >5/50 HPF (high-power field) mitotic activity. The postoperative course was uneventful, and the coagulopathy improved rapidly. CONCLUSION: Since the characteristic of tumor in this case was hypervascularity with bleeding and necrotic lesions, coagulopathy was thought to be caused by the trapping of platelets within a large vasculized tumor mass. BioMed Central 2007-06-01 /pmc/articles/PMC1892781/ /pubmed/17540038 http://dx.doi.org/10.1186/1477-7819-5-59 Text en Copyright © 2007 Watanabe et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Watanabe, Taiji Segami, Kohei Sasaki, Takahiro Kawashima, Hatsuya Enomoto, Takeharu Jinnouchi, Yuji Koizumi, Satoshi Tobe, Naotaka Sakurai, Joh Shimamura, Tsukasa Suda, Tadashi Asakura, Takeshi Nakano, Hiroshi Ichiroh, Tanaka Otsubo, Takehito A rare case of concomitant huge exophytic gastrointestinal stromal tumor of the stomach and Kasabach-Merritt phenomenon |
title | A rare case of concomitant huge exophytic gastrointestinal stromal tumor of the stomach and Kasabach-Merritt phenomenon |
title_full | A rare case of concomitant huge exophytic gastrointestinal stromal tumor of the stomach and Kasabach-Merritt phenomenon |
title_fullStr | A rare case of concomitant huge exophytic gastrointestinal stromal tumor of the stomach and Kasabach-Merritt phenomenon |
title_full_unstemmed | A rare case of concomitant huge exophytic gastrointestinal stromal tumor of the stomach and Kasabach-Merritt phenomenon |
title_short | A rare case of concomitant huge exophytic gastrointestinal stromal tumor of the stomach and Kasabach-Merritt phenomenon |
title_sort | rare case of concomitant huge exophytic gastrointestinal stromal tumor of the stomach and kasabach-merritt phenomenon |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892781/ https://www.ncbi.nlm.nih.gov/pubmed/17540038 http://dx.doi.org/10.1186/1477-7819-5-59 |
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