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Secreted Sulfatases Sulf1 and Sulf2 Have Overlapping yet Essential Roles in Mouse Neonatal Survival

BACKGROUND: Heparan sulfate proteoglycans (HSPGs) use highly sulfated polysaccharide side-chains to interact with several key growth factors and morphogens, thereby regulating their accessibility and biological activity. Various sulfotransferases and sulfatases with differing specificities control t...

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Detalles Bibliográficos
Autores principales: Holst, Charles R., Bou-Reslan, Hani, Gore, Bryan B., Wong, Karen, Grant, Deanna, Chalasani, Sreedevi, Carano, Richard A., Frantz, Gretchen D., Tessier-Lavigne, Marc, Bolon, Brad, French, Dorothy M., Ashkenazi, Avi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892809/
https://www.ncbi.nlm.nih.gov/pubmed/17593974
http://dx.doi.org/10.1371/journal.pone.0000575