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Secreted Sulfatases Sulf1 and Sulf2 Have Overlapping yet Essential Roles in Mouse Neonatal Survival
BACKGROUND: Heparan sulfate proteoglycans (HSPGs) use highly sulfated polysaccharide side-chains to interact with several key growth factors and morphogens, thereby regulating their accessibility and biological activity. Various sulfotransferases and sulfatases with differing specificities control t...
Autores principales: | Holst, Charles R., Bou-Reslan, Hani, Gore, Bryan B., Wong, Karen, Grant, Deanna, Chalasani, Sreedevi, Carano, Richard A., Frantz, Gretchen D., Tessier-Lavigne, Marc, Bolon, Brad, French, Dorothy M., Ashkenazi, Avi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892809/ https://www.ncbi.nlm.nih.gov/pubmed/17593974 http://dx.doi.org/10.1371/journal.pone.0000575 |
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