Psychometric properties of a prostate cancer radiation late toxicity questionnaire

BACKGROUND: To construct a short prostate cancer radiation late toxicity (PCRT) questionnaire with health-related quality-of-life (HRQoL) domains. METHODS: The PCRT was developed by item generation, questionnaire construction (n = 7 experts, n = 8 focus group patients), pilot testing (n = 37), item...

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Detalles Bibliográficos
Autores principales: Rodrigues, George, Bauman, Glenn, Lock, Michael, D'Souza, David, Mahon, Jeff
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894787/
https://www.ncbi.nlm.nih.gov/pubmed/17540022
http://dx.doi.org/10.1186/1477-7525-5-29
Descripción
Sumario:BACKGROUND: To construct a short prostate cancer radiation late toxicity (PCRT) questionnaire with health-related quality-of-life (HRQoL) domains. METHODS: The PCRT was developed by item generation, questionnaire construction (n = 7 experts, n = 8 focus group patients), pilot testing (n = 37), item reduction (n = 100), reliability testing (n = 237), and validity testing (n = 274). RESULTS: Reliability of the three item-reduced subscales demonstrated intraclass correlation coefficients (CC) of 0.811 (GU), 0.842 (GI), and 0.740 (sexual). Discriminant validity demonstrated Pearson CC of 0.449 (GU-GI), 0.200 (sexual-GU), and 0.09 (sexual-GI). Content validity correlations between PCRT-PCQoL were 0.35–0.78, PCRT-FACT-G(© )were 0.19–0.39, and PCRT-SF-36(® )were 0.03–0.34. CONCLUSION: We successfully generated a PCRT HRQoL questionnaire including subscales with very good psychometric properties.

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