Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution

BACKGROUND: Non-ribosomal peptide synthetases (NRPSs) are large multimodular enzymes that synthesize a wide range of biologically active natural peptide compounds, of which many are pharmacologically important. Peptide bond formation is catalyzed by the Condensation (C) domain. Various functional su...

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Detalles Bibliográficos
Autores principales: Rausch, Christian, Hoof, Ilka, Weber, Tilmann, Wohlleben, Wolfgang, Huson, Daniel H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894796/
https://www.ncbi.nlm.nih.gov/pubmed/17506888
http://dx.doi.org/10.1186/1471-2148-7-78

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894796/
https://www.ncbi.nlm.nih.gov/pubmed/17506888
http://dx.doi.org/10.1186/1471-2148-7-78

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