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Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution
BACKGROUND: Non-ribosomal peptide synthetases (NRPSs) are large multimodular enzymes that synthesize a wide range of biologically active natural peptide compounds, of which many are pharmacologically important. Peptide bond formation is catalyzed by the Condensation (C) domain. Various functional su...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894796/ https://www.ncbi.nlm.nih.gov/pubmed/17506888 http://dx.doi.org/10.1186/1471-2148-7-78 |