Is there an alternative to increasing the sample size in microarray studies?

Our answer to the question posed in the title is negative. This intentionally provocative note discusses the issue of sample size in microarray studies from several angles. We suggest that the current view of microarrays as no more than a screening tool be changed and small sample studies no longer...

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Detalles Bibliográficos
Autores principales: Klebanov, Lev, Yakovlev, Andrei
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2007
Materias:
Views & Challenges
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1896058/
https://www.ncbi.nlm.nih.gov/pubmed/17597934
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author Klebanov, Lev
Yakovlev, Andrei
author_facet Klebanov, Lev
Yakovlev, Andrei
author_sort Klebanov, Lev
collection PubMed
description Our answer to the question posed in the title is negative. This intentionally provocative note discusses the issue of sample size in microarray studies from several angles. We suggest that the current view of microarrays as no more than a screening tool be changed and small sample studies no longer be considered appropriate.
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spelling pubmed-18960582007-06-27 Is there an alternative to increasing the sample size in microarray studies? Klebanov, Lev Yakovlev, Andrei Bioinformation Views & Challenges Our answer to the question posed in the title is negative. This intentionally provocative note discusses the issue of sample size in microarray studies from several angles. We suggest that the current view of microarrays as no more than a screening tool be changed and small sample studies no longer be considered appropriate. Biomedical Informatics Publishing Group 2007-04-10 /pmc/articles/PMC1896058/ /pubmed/17597934 Text en © 2006 Biomedical Informatics Publishing Group This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
spellingShingle Views & Challenges
Klebanov, Lev
Yakovlev, Andrei
Is there an alternative to increasing the sample size in microarray studies?
title Is there an alternative to increasing the sample size in microarray studies?
title_full Is there an alternative to increasing the sample size in microarray studies?
title_fullStr Is there an alternative to increasing the sample size in microarray studies?
title_full_unstemmed Is there an alternative to increasing the sample size in microarray studies?
title_short Is there an alternative to increasing the sample size in microarray studies?
title_sort is there an alternative to increasing the sample size in microarray studies?
topic Views & Challenges
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1896058/
https://www.ncbi.nlm.nih.gov/pubmed/17597934
work_keys_str_mv AT klebanovlev isthereanalternativetoincreasingthesamplesizeinmicroarraystudies
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