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160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
BACKGROUND: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching sequence databases that may contain hundreds of millions of sequences, this algorithm becomes computationally expensive. R...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1896180/ https://www.ncbi.nlm.nih.gov/pubmed/17555593 http://dx.doi.org/10.1186/1471-2105-8-185 |