Transcription Factor NF-κB Is Transported to the Nucleus via Cytoplasmic Dynein/Dynactin Motor Complex in Hippocampal Neurons

BACKGROUND: Long-term changes in synaptic plasticity require gene transcription, indicating that signals generated at the synapse must be transported to the nucleus. Synaptic activation of hippocampal neurons is known to trigger retrograde transport of transcription factor NF-κB. Transcription facto...

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Detalles Bibliográficos
Autores principales: Mikenberg, Ilja, Widera, Darius, Kaus, Aljoscha, Kaltschmidt, Barbara, Kaltschmidt, Christian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899224/
https://www.ncbi.nlm.nih.gov/pubmed/17622342
http://dx.doi.org/10.1371/journal.pone.0000589

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