Activation of Akt is increased in the dysplasia-carcinoma sequence in Barrett's oesophagus and contributes to increased proliferation and inhibition of apoptosis: a histopathological and functional study

BACKGROUND: The incidence of oesophageal adenocarcinoma is increasing rapidly in the developed world. The serine-threonine protein kinase and proto-oncogene Akt has been reported to regulate proliferation and apoptosis in several tissues but there are no data on the involvement of Akt in oesophageal...

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Detalles Bibliográficos
Autores principales: Beales, Ian LP, Ogunwobi, Olorunseun, Cameron, Ewen, El-Amin, Khalid, Mutungi, Gabriel, Wilkinson, Mark
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899509/
https://www.ncbi.nlm.nih.gov/pubmed/17559672
http://dx.doi.org/10.1186/1471-2407-7-97

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