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Novel oligodeoxynucleotide agonists of TLR9 containing N(3)-Me-dC or N(1)-Me-dG modifications

Synthetic oligodeoxynucleotides containing unmethylated CpG motifs activate Toll-Like Receptor 9 (TLR9). Our previous studies have shown the role of hydrogen-bond donor and acceptor groups of cytosine and guanine in the CpG motif and identified synthetic immunostimulatory motifs. In the present stud...

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Detalles Bibliográficos
Autores principales:	Putta, Mallikarjuna Reddy, Zhu, FuGang, Li, Yukui, Bhagat, Lakshmi, Cong, YanPing, Kandimalla, Ekambar R., Agrawal, Sudhir
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904100/ https://www.ncbi.nlm.nih.gov/pubmed/16798912 http://dx.doi.org/10.1093/nar/gkl430

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