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Short, synthetic and selectively (13)C-labeled RNA sequences for the NMR structure determination of protein–RNA complexes
We report an optimized synthesis of all canonical 2′-O-TOM protected ribonucleoside phosphoramidites and solid supports containing [(13)C(5)]-labeled ribose moieties, their sequence-specific introduction into very short RNA sequences and their use for the structure determination of two protein–RNA c...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904103/ https://www.ncbi.nlm.nih.gov/pubmed/16807315 http://dx.doi.org/10.1093/nar/gkl427 |