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Rejection of large HPV-16 expressing tumors in aged mice by a single immunization of VacciMax(® )encapsulated CTL/T helper peptides
The incidence of cancer increases significantly in later life, yet few pre-clinical studies of cancer immunotherapy use mice of advanced age. A novel vaccine delivery platform (VacciMax(®),VM) is described that encapsulates antigens and adjuvants in multilamellar liposomes in a water-in-oil emulsion...
Autores principales: | Daftarian, Pirouz M, Mansour, Marc, Pohajdak, Bill, Fuentes-Ortega, Antar, Korets-Smith, Ella, MacDonald, Lisa, Weir, Genevieve, Brown, Robert G, Kast, W Martin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904180/ https://www.ncbi.nlm.nih.gov/pubmed/17555571 http://dx.doi.org/10.1186/1479-5876-5-26 |
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