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The stochastic behavior of a molecular switching circuit with feedback
BACKGROUND: Using a statistical physics approach, we study the stochastic switching behavior of a model circuit of multisite phosphorylation and dephosphorylation with feedback. The circuit consists of a kinase and phosphatase acting on multiple sites of a substrate that, contingent on its modificat...
Autores principales: | Krishnamurthy, Supriya, Smith, Eric, Krakauer, David, Fontana, Walter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904185/ https://www.ncbi.nlm.nih.gov/pubmed/17540019 http://dx.doi.org/10.1186/1745-6150-2-13 |
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