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Malarial pigment haemozoin, IFN-gamma, TNF-alpha, IL-1beta and LPS do not stimulate expression of inducible nitric oxide synthase and production of nitric oxide in immuno-purified human monocytes
BACKGROUND: Enhanced production of nitric oxide (NO) following upmodulation of the inducible isoform of NO synthase (iNOS) by haemozoin (HZ), inflammatory cytokines and LPS may provide protection against Plasmodium falciparum malaria by killing hepatic and blood forms of parasites and inhibiting the...
Autores principales: | Skorokhod, Oleksii A, Schwarzer, Evelin, Ceretto, Monica, Arese, Paolo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904226/ https://www.ncbi.nlm.nih.gov/pubmed/17543124 http://dx.doi.org/10.1186/1475-2875-6-73 |
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