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Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-κB, JNK1, p53 and WOX1 during stress response

BACKGROUND: Zfra is a 31-amino-acid zinc finger-like protein, which is known to regulate cell death by tumor necrosis factor (TNF) and overexpressed TNF receptor- or Fas-associated death domain proteins (TRADD and FADD). In addition, Zfra undergoes self-association and interacts with c-Jun N-termina...

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Detalles Bibliográficos
Autores principales: Hong, Qunying, Hsu, Li-Jin, Schultz, Lori, Pratt, Nicole, Mattison, Jeffrey, Chang, Nan-Shan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904229/
https://www.ncbi.nlm.nih.gov/pubmed/17567906
http://dx.doi.org/10.1186/1471-2199-8-50