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Hin-mediated DNA knotting and recombining promote replicon dysfunction and mutation

BACKGROUND: The genetic code imposes a dilemma for cells. The DNA must be long enough to encode for the complexity of an organism, yet thin and flexible enough to fit within the cell. The combination of these properties greatly favors DNA collisions, which can knot and drive recombination of the DNA...

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Detalles Bibliográficos
Autores principales: Deibler, Richard W, Mann, Jennifer K, Sumners, De Witt L, Zechiedrich, Lynn
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904230/
https://www.ncbi.nlm.nih.gov/pubmed/17531098
http://dx.doi.org/10.1186/1471-2199-8-44