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Hin-mediated DNA knotting and recombining promote replicon dysfunction and mutation
BACKGROUND: The genetic code imposes a dilemma for cells. The DNA must be long enough to encode for the complexity of an organism, yet thin and flexible enough to fit within the cell. The combination of these properties greatly favors DNA collisions, which can knot and drive recombination of the DNA...
Autores principales: | Deibler, Richard W, Mann, Jennifer K, Sumners, De Witt L, Zechiedrich, Lynn |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904230/ https://www.ncbi.nlm.nih.gov/pubmed/17531098 http://dx.doi.org/10.1186/1471-2199-8-44 |
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