A real-time view of the TAR:Tat:P-TEFb complex at HIV-1 transcription sites

HIV-1 transcription is tightly regulated: silent in long-term latency and highly active in acutely-infected cells. Transcription is activated by the viral protein Tat, which recruits the elongation factor P-TEFb by binding the TAR sequence present in nascent HIV-1 RNAs. In this study, we analyzed th...

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Detalles Bibliográficos
Autores principales: Molle, Dorothée, Maiuri, Paolo, Boireau, Stéphanie, Bertrand, Edouard, Knezevich, Anna, Marcello, Alessandro, Basyuk, Eugenia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904240/
https://www.ncbi.nlm.nih.gov/pubmed/17537237
http://dx.doi.org/10.1186/1742-4690-4-36

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