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A Structural Split in the Human Genome
BACKGROUND: Promoter-associated CpG islands (PCIs) mediate methylation-dependent gene silencing, yet tend to co-locate to transcriptionally active genes. To address this paradox, we used data mining to assess the behavior of PCI-positive (PCI+) genes in the human genome. RESULTS: PCI+ genes exhibit...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904255/ https://www.ncbi.nlm.nih.gov/pubmed/17622348 http://dx.doi.org/10.1371/journal.pone.0000603 |