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Loss of Robustness and Addiction to IGF1 during Early Keratinocyte Transformation by Human Papilloma Virus 16

Infection of keratinocytes with high risk human Papilloma virus causes immortalization, and when followed by further mutations, leads to cervical cancer and other anogenital tumors. Here we monitor the progressive loss of robustness in an in vitro model of the early stages of transformation that com...

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Detalles Bibliográficos
Autores principales: Geiger, Tamar, Levitzki, Alexander
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904256/
https://www.ncbi.nlm.nih.gov/pubmed/17622350
http://dx.doi.org/10.1371/journal.pone.0000605