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Interplay between DNA N-glycosylases/AP lyases at multiply damaged sites and biological consequences
Evidence has emerged that repair of clustered DNA lesions may be compromised, possibly leading to the formation of double-strand breaks (DSB) and, thus, to deleterious events. The first repair event occurring at a multiply damaged site (MDS) is of major importance and will largely contribute to the...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904269/ https://www.ncbi.nlm.nih.gov/pubmed/17468500 http://dx.doi.org/10.1093/nar/gkm190 |