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Interplay between DNA N-glycosylases/AP lyases at multiply damaged sites and biological consequences

Evidence has emerged that repair of clustered DNA lesions may be compromised, possibly leading to the formation of double-strand breaks (DSB) and, thus, to deleterious events. The first repair event occurring at a multiply damaged site (MDS) is of major importance and will largely contribute to the...

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Detalles Bibliográficos
Autores principales: Éot-Houllier, Grégory, Gonera, Marta, Gasparutto, Didier, Giustranti, Céline, Sage, Evelyne
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904269/
https://www.ncbi.nlm.nih.gov/pubmed/17468500
http://dx.doi.org/10.1093/nar/gkm190

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