Primate TNF Promoters Reveal Markers of Phylogeny and Evolution of Innate Immunity

BACKGROUND: Tumor necrosis factor (TNF) is a critical cytokine in the immune response whose transcriptional activation is controlled by a proximal promoter region that is highly conserved in mammals and, in particular, primates. Specific single nucleotide polymorphisms (SNPs) upstream of the proxima...

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Detalles Bibliográficos
Autores principales: Baena, Andres, Mootnick, Alan R., Falvo, James V., Tsytsykova, Alla V., Ligeiro, Filipa, Diop, Ousmane M., Brieva, Claudia, Gagneux, Pascal, O'Brien, Stephen J., Ryder, Oliver A., Goldfeld, Anne E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1905939/
https://www.ncbi.nlm.nih.gov/pubmed/17637837
http://dx.doi.org/10.1371/journal.pone.0000621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1905939/
https://www.ncbi.nlm.nih.gov/pubmed/17637837
http://dx.doi.org/10.1371/journal.pone.0000621

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