Cytosolic and ER J-domains of mammalian and parasitic origin can functionally interact with DnaK

Both prokaryotic and eukaryotic cells contain multiple heat shock protein 40 (Hsp40) and heat shock protein 70 (Hsp70) proteins, which cooperate as molecular chaperones to ensure fidelity at all stages of protein biogenesis. The Hsp40 signature domain, the J-domain, is required for binding of an Hsp...

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Detalles Bibliográficos
Autores principales: Nicoll, W.S., Botha, M., McNamara, C., Schlange, M., Pesce, E.-R., Boshoff, A., Ludewig, M.H., Zimmermann, R., Cheetham, M.E., Chapple, J.P., Blatch, G.L.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906734/
https://www.ncbi.nlm.nih.gov/pubmed/17239655
http://dx.doi.org/10.1016/j.biocel.2006.11.006

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