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Lack of association between the chemokine receptor 5 polymorphism CCR5delta32 in rheumatoid arthritis and juvenile idiopathic arthritis

BACKGROUND: The chemokine receptor CCR5 has been detected at elevated levels on synovial T cells, and a 32 bp deletion in the CCR5 gene leads to a non-functional receptor. A negative association between the CCR5Δ32 and rheumatoid arthritis (RA) has been reported, although with conflicting results. I...

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Detalles Bibliográficos
Autores principales: Lindner, Ewald, Nordang, Gry BN, Melum, Espen, Flatø, Berit, Selvaag, Anne Marit, Thorsby, Erik, Kvien, Tore K, Førre, Øystein T, Lie, Benedicte A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906748/
https://www.ncbi.nlm.nih.gov/pubmed/17565662
http://dx.doi.org/10.1186/1471-2350-8-33