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Hyperglycemia regulates thioredoxin-ROS activity through induction of thioredoxin-interacting protein (TXNIP) in metastatic breast cancer-derived cells MDA-MB-231

BACKGROUND: We studied the RNA expression of the genes in response to glucose from 5 mM (condition of normoglycemia) to 20 mM (condition of hyperglycemia/diabetes) by microarray analysis in breast cancer derived cell line MDA-MB-231. We identified the thioredoxin-interacting protein (TXNIP), whose R...

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Detalles Bibliográficos
Autores principales:	Turturro, Francesco, Friday, Ellen, Welbourne, Tomas
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906826/ https://www.ncbi.nlm.nih.gov/pubmed/17555594 http://dx.doi.org/10.1186/1471-2407-7-96

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