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In vivo optical imaging of integrin α(V)-β(3 )in mice using multivalent or monovalent cRGD targeting vectors
BACKGROUND: The cRGD peptide is a promising probe for early non-invasive detection of tumors. This study aimed to demonstrate how RAFT-c(-RGDfK-)(4), a molecule allowing a tetrameric presentation of cRGD, improved cRGD-targeting potential using in vivo models of α(V)β(3)-positive or negative tumors....
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906830/ https://www.ncbi.nlm.nih.gov/pubmed/17565663 http://dx.doi.org/10.1186/1476-4598-6-41 |